Nagasaka H, Aikawa K, Hayashi K, Sugai M, Murakami Y, Ohara K, Nakamura S, Matsumoto N, Matsumoto I, Hori T
Department of Anesthesia, Ogawa Red Cross Hospital, Saitama.
Masui. 1992 Apr;41(4):649-54.
To discover the influence of age on spinal blockade with plain bupivacaine, 23 patients were administered a subarachnoid injection of approximately 4.0 ml of 0.5% bupivacaine. The patients were divided into two groups. One group consists of patients with ages under 65 years (younger group, n = 13), and the other group consists of patients older than 65 years (elder group, n = 10). The following results were obtained. The time to onset of anesthetic effects (pinprick discrimination, temperature discrimination, and light touch discrimination) decreased with age. At 180 min after the administration, spinal blockade level did not have a significant difference. The degree of the decrease of systolic arterial pressure was greater in the elder group than in the younger group. However, the degree of the decrease of heart rate was greater in the elder group than in the younger group.
为探究年龄对布比卡因腰麻的影响,对23例患者进行蛛网膜下腔注射约4.0毫升0.5%布比卡因。患者分为两组。一组为年龄在65岁以下的患者(年轻组,n = 13),另一组为年龄大于65岁的患者(老年组,n = 10)。得到以下结果。麻醉效果(针刺觉、温度觉和轻触觉)的起效时间随年龄增长而缩短。给药后180分钟,腰麻平面无显著差异。老年组收缩压下降程度大于年轻组。然而,老年组心率下降程度大于年轻组。