Amon M, Menapace R
Universitäts-Augenklinik, Wien.
Klin Monbl Augenheilkd. 1992 Feb;200(2):95-100. doi: 10.1055/s-2008-1045719.
In order to find a difference in the biocompatibility of different IOL-materials we examined the lens-surface of poly(methylmetacrylate)-(PMMA-), heparin surface-modified PMMA-(HSM-PMMA-) and hydrogel-IOLs in a prospective study by specular microscopy. Documentation consisted of cellular reaction, precipitates on the lens-surface and irregularities of the IOL-material. Early postoperative on HSM-PMMA and hydrogel-IOLs there were fewer fibroblast-like cells as compared to PMMA-IOLs. In the later postoperative period foreign body giant cells were seen on PMMA-IOLs in 26.6%, on HSM-PMMA and hydrogel-IOLs in less than 10% of the cases. In cases with increased postoperative inflammation or contact between uveal tissue and lens-surface we found more cells and in a higher percentage. Concerning precipitates on the surface and material irregularities we also found lens-specific differences. Clinical results were satisfactory for all lens-types.
为了找出不同人工晶状体材料生物相容性的差异，我们在一项前瞻性研究中通过镜面显微镜检查了聚甲基丙烯酸甲酯（PMMA）、肝素表面改性的PMMA（HSM-PMMA）和水凝胶人工晶状体的晶状体表面。记录内容包括细胞反应、晶状体表面的沉淀物以及人工晶状体材料的不规则情况。术后早期，与PMMA人工晶状体相比，HSM-PMMA和水凝胶人工晶状体上的成纤维细胞样细胞较少。在术后后期，26.6%的PMMA人工晶状体上可见异物巨细胞，HSM-PMMA和水凝胶人工晶状体上该比例不到10%。在术后炎症加重或葡萄膜组织与晶状体表面接触的情况下，我们发现细胞更多且比例更高。关于表面沉淀物和材料不规则情况，我们也发现了晶状体特异性差异。所有晶状体类型的临床结果均令人满意。
