Cornelius Jack R, Clark Duncan B, Bukstein Oscar G, Salloum Ihsan M
School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213-2593, USA.
Recent Dev Alcohol. 2005;17:349-65. doi: 10.1007/0-306-48626-1_16.
Comorbid psychiatric disorders and drug use disorders (DUDs) are common among adolescents with alcohol use disorders (AUDs). These comorbid disorders have a large potential significance on the clinical course of the AUDs among adolescents, and can predict a shorter time to relapse of alcohol use. The use of medication for treatment of the various comorbid adolescent populations has increased dramatically in recent years, despite the lack of double-blind, placebo-controlled studies that demonstrate their safety and efficacy. Consequently, to date, no empirically proven treatment exists for most of these comorbid disorders. This chapter reviews the state of the art regarding the treatment of comorbid adolescents. This chapter also identifies gaps in knowledge regarding the treatment of comorbid adolescents, and outlines directions for future research in this field.
共病精神障碍和药物使用障碍(DUDs)在患有酒精使用障碍(AUDs)的青少年中很常见。这些共病障碍对青少年酒精使用障碍的临床病程具有很大的潜在意义,并且可以预测酒精使用复发的时间更短。尽管缺乏双盲、安慰剂对照研究来证明其安全性和有效性,但近年来用于治疗各种共病青少年人群的药物使用显著增加。因此,迄今为止,对于大多数这些共病障碍尚无经实证验证的治疗方法。本章回顾了关于共病青少年治疗的最新进展。本章还指出了关于共病青少年治疗的知识空白,并概述了该领域未来的研究方向。