Sameshima Hiroshi, Nagai Kimihiro, Ikenoue Tsuyomu
Department of Obstetrics and Gynecology, Miyazaki Medical College, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki 889-1692, Japan.
Gynecol Oncol. 2005 Apr;97(1):276-8. doi: 10.1016/j.ygyno.2004.12.012.
Congenital anomalies arising from the urogenital tracts are common. We experienced two cases of specific urogenital anomalies.
Two Japanese women had a single ectopic ureter opening in the central wall of the vagina, ipsilateral kidney agenesis, and ipsilateral rudimentary uterine horn of the bicornuate uterus. One had squamous cell carcinoma of the uterine cervix, and the other had adenocarcinoma of the vagina arising from the ectopic ureter meatus, which was histologically confirmed as fetal metanephric duct remnant. One had vesico-vaginal fistula postoperatively, resulting from separating the ureter-like duct from the bladder.
Concomitant occurrence of anomalies suggests the common genetic backgrounds, which are not well known. Clinically, the ectopic vaginal ureter is important as a possible background of vaginal adenocarcinoma, and information on the ureter-like duct course is required during surgery.
泌尿生殖道先天性异常很常见。我们遇到了两例特殊的泌尿生殖道异常病例。
两名日本女性阴道中壁有单一异位输尿管开口、同侧肾缺如以及双角子宫的同侧残角子宫。其中一名患有子宫颈鳞状细胞癌,另一名患有源于异位输尿管口的阴道腺癌,组织学证实为胎儿后肾管残余。其中一名术后出现膀胱阴道瘘,是由于将输尿管样管道与膀胱分离所致。
多种异常同时出现提示存在尚不明确的共同遗传背景。临床上,异位阴道输尿管作为阴道腺癌的可能背景很重要,手术期间需要了解输尿管样管道的走行信息。