Oh Seung-June, Ku Ja Hyeon, Hong Sung Kyu, Kim Soo Woong, Paick Jae-Seung, Son Hwancheol
Department of Urology, Seoul National University College of Medicine and Seoul National University Hospital, Seoul, Korea.
Neurourol Urodyn. 2005;24(4):341-7. doi: 10.1002/nau.20130.
The aim of this study was to assess the impact of patient-perceived disease severity (PPDS) on the quality of life (QoL) of women with urinary incontinence (UI) and to identify factors predicting PPDS.
A total of 109 women (mean age 54.9; range 31-77) with stress UI combined with or without urge UI were included in the primary analyses. The incontinence quality of life (I-QoL) devised during the course of this study was used to assess the QOL impact of UI.
PPDS of women with UI increased as I-QoL scores decreased (P<0.001). When analyzed by patient characteristics and objective test results, PPDS increased only with the number of episodes (P=0.005) and pad test weight increased (P=0.010). By multivariate regression analysis, patients who complained of UI "three to four times a day or more" had 6.4-fold higher risk (P=0.027) of perceiving that their symptoms were more severe than those who complained of a UI "one to two times per week or less." Patients with a pad test weight of >25 g had a 4.7-fold higher risk of perceiving their symptoms were more severe than those with a pad test weight of <15 g.
Our results suggest that the frequency of UI episodes and the volume of urine loss are associated with PPDS. In addition, the I-QoL scores deteriorated significantly as the PPDS of incontinence increased. Thus, PPDS may impact on the QoL of women with stress UI combined with or without urge UI.
本研究旨在评估患者感知的疾病严重程度(PPDS)对尿失禁(UI)女性生活质量(QoL)的影响,并确定预测PPDS的因素。
共有109名患有压力性尿失禁合并或不合并急迫性尿失禁的女性(平均年龄54.9岁;范围31 - 77岁)纳入主要分析。本研究过程中设计的尿失禁生活质量(I-QoL)用于评估尿失禁对生活质量的影响。
尿失禁女性的PPDS随着I-QoL评分降低而增加(P<0.001)。按患者特征和客观测试结果分析时,PPDS仅随发作次数增加(P = 0.005)以及尿垫试验重量增加(P = 0.010)而增加。通过多因素回归分析,抱怨尿失禁“每天三到四次或更多”的患者认为其症状比抱怨尿失禁“每周一到两次或更少”的患者严重的风险高6.4倍(P = 0.027)。尿垫试验重量>25 g的患者认为其症状比尿垫试验重量<15 g的患者严重的风险高4.7倍。
我们的结果表明,尿失禁发作频率和尿量损失与PPDS相关。此外,随着尿失禁PPDS增加,I-QoL评分显著恶化。因此,PPDS可能会影响合并或不合并急迫性尿失禁的压力性尿失禁女性的生活质量。