Vegunta Ravindra K, Wallace Lizabeth J, Leonardi Michael R, Gross Tom L, Renfroe Yolanda, Marshall J Stephen, Cohen Howard S, Hocker James R, Macwan Kamlesh S, Clark Sue E, Ramiro Susan, Pearl Richard H
Department of Surgery, University of Illinois College of Medicine, Peoria, IL 61603, USA.
J Pediatr Surg. 2005 Mar;40(3):528-34. doi: 10.1016/j.jpedsurg.2004.11.037.
The authors developed a clinical pathway for optimal management after antenatal diagnosis of gastroschisis. This is the outcomes analysis of our first 30 consecutive patients.
Antenatal counseling was provided for all families with in-utero diagnosis of gastroschisis. Bowel dilatation, thickness, motility, amniotic fluid volume, and fetal development were followed by ultrasonography every 4 weeks. Babies were delivered by cesarean section between 36 and 38 weeks gestation if the lungs were mature or earlier for bowel complications. Gastroschisis repair was scheduled 90 minutes after birth. Primary repair was attempted in all through the abdominal wall defect without an additional incision, resulting in an umbilicus with no abdominal scar.
Primary repair was achieved in 83%. Babies needed assisted ventilation for 3 days, reached full feeds by 19 days, and were discharged by 24 days (all medians). There were 3 (10%) deaths, all after staged repair.
Our new protocol of both scheduled elective cesarean section and early gastroschisis repair resulted in a higher proportion of primary repair, shorter duration of mechanical ventilation, earlier full feeds, and shorter length of stay. There was no increase in mortality or morbidity. The primary-repair babies had no mortality and had excellent cosmesis.
作者制定了一种产前诊断腹裂后优化管理的临床路径。这是对我们连续收治的首批30例患者的结果分析。
为所有产前诊断为腹裂的家庭提供咨询。每4周通过超声检查监测肠管扩张、厚度、蠕动、羊水量和胎儿发育情况。如果肺部成熟,妊娠36至38周之间行剖宫产分娩,若出现肠道并发症则提前分娩。腹裂修补术安排在出生后90分钟进行。所有患儿均尝试通过腹壁缺损进行一期修补,无需额外切口,术后脐部无腹部瘢痕。
83%的患儿实现了一期修补。患儿需要辅助通气3天,19天达到完全经口喂养,24天出院(均为中位数)。有3例(10%)死亡,均为分期修补术后。
我们制定的择期剖宫产和早期腹裂修补的新方案,使一期修补比例更高,机械通气时间更短,完全经口喂养更早,住院时间更短。死亡率和发病率没有增加。接受一期修补的患儿无死亡,且美容效果极佳。