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[腹裂。早产择期剖宫产及一期直接缝合:我们的经验]

[Gastroschisis. Preterm elective cesarean and immediate primary closure: our experience].

作者信息

Glasmeyer P, Grande C, Margarit J, Martí M, Torino J R, Mirada A, Sans A

机构信息

Servicio de Cirugía Pediátrica, Hospital Mútua de Terrassa.

出版信息

Cir Pediatr. 2012 Jan;25(1):12-5.

PMID:23113406
Abstract

PURPOSE

Our experience en treatment of gastroschisis using a protocol with elective preterm delivery by caesarean section at 34-35 weeks and immediate primary abdominal wall closure.

METHODS

During a period of 18 month we treated 5 patients with gastroschisis using the following management pathway: Starting at 30th week of gestation, weekly ultrasound evaluation of fetal gut and pulmonary maturation with corticosteroids. Delivery by elective caesarean section between 34-35 weeks or earlier if evidence of bowel compromise was reported en ultrasound study. Immediate surgical correction after birth with primary closure was preformed under control of abdominal pressure.

RESULTS

Mean gestational age of our patient was 33,94 weeks, and mean birth weight was 2154 gr. None of the cases present inflammatory peel and we found no difficulties for reduction of the gut at time of surgery. Two patients presented an intestinal malrotation. Extubation was preformed 36-48 hours after surgery. We started a trofic diet at 3,6 days and parental nutrition was retired after a mean period of 15,8 days. The mean time of hospital stay was 33,4 days. One patient with intestinal obstruction had a consideriously increased length of hospital stay of 74 days.

CONCLUSIONS

A management pathway for gastroschisis with selective preterm delivery by caesarean section and immediate surgical treatment probably reduces the experience of inflammatory peel. This pathway permits a early initiation of oral feeding, reduces times of parenteral nutrition and need of central catheters, and shortens length of hospital stay.

摘要

目的

我们采用一种方案治疗腹裂,该方案包括在34 - 35周选择性剖宫产早产并立即进行一期腹壁关闭。

方法

在18个月的时间里,我们对5例腹裂患者采用了以下管理路径:从妊娠第30周开始,每周进行超声评估胎儿肠道和肺成熟情况,并使用皮质类固醇。如果超声检查报告有肠损伤迹象,则在34 - 35周或更早进行选择性剖宫产。出生后立即在控制腹压的情况下进行手术矫正并一期关闭。

结果

我们患者的平均孕周为33.94周,平均出生体重为2154克。所有病例均未出现炎性粘连,手术时肠道还纳未遇到困难。2例患者出现肠旋转不良。术后36 - 48小时拔管。术后3.6天开始经口喂养,平均15.8天后停止肠外营养。平均住院时间为33.4天。1例肠梗阻患者的住院时间显著延长至74天。

结论

腹裂的管理路径采用选择性剖宫产早产并立即进行手术治疗,可能会减少炎性粘连的发生。该路径允许早期开始经口喂养,减少肠外营养时间和中心静脉导管的需求,并缩短住院时间。

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1
[Gastroschisis. Preterm elective cesarean and immediate primary closure: our experience].[腹裂。早产择期剖宫产及一期直接缝合:我们的经验]
Cir Pediatr. 2012 Jan;25(1):12-5.
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Immediate versus silo closure for gastroschisis: Results of a large multicenter study.立即关闭与间隔关闭治疗先天性腹裂的对比:一项大型多中心研究结果。
J Pediatr Surg. 2020 Jul;55(7):1280-1285. doi: 10.1016/j.jpedsurg.2019.08.002. Epub 2019 Aug 22.
2
Fetal anterior abdominal wall defects: prenatal imaging by magnetic resonance imaging.胎儿前腹壁缺陷:磁共振成像的产前影像学检查
Pediatr Radiol. 2018 Apr;48(4):499-512. doi: 10.1007/s00247-017-3914-x. Epub 2018 Mar 17.
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Outcomes in infants with prenatally diagnosed gastroschisis and planned preterm delivery.
产前诊断为腹裂并计划早产的婴儿的结局
Pediatr Surg Int. 2015 Nov;31(11):1047-53. doi: 10.1007/s00383-015-3795-8. Epub 2015 Sep 23.