SF-36健康状况问卷在评估遗传性出血性毛细血管扩张症继发鼻出血患者中的应用
The SF-36 health status questionnaire in assessing patients with epistaxis secondary to hereditary hemorrhagic telangiectasia.
作者信息
Lennox Penelope A, Hitchings Anne E, Lund Valerie J, Howard David J
机构信息
Professorial Unit, The Royal National Throat Nose and Ear Hospital, London, United Kingdom.
出版信息
Am J Rhinol. 2005 Jan-Feb;19(1):71-4.
BACKGROUND
This study assesses the ability of the short form 36 (SF-36), a validated health status survey, to measure the health of patients with epistaxis due to hereditary hemorrhagic telangiectasia (HHT).
METHODS
Thirty-eight patients completed the SF-36 and symptom-specific questionnaires. They were asked to rate their epistaxis as severe, moderate, or mild. The SF-36 data are compared with a reference population and analyzed with respect to the subgroups.
RESULTS
The scores for each dimension of health were significantly reduced (p < 0.05) when compared with the reference population for all dimensions except pain. When compared with the patients' ratings of severity, a significant correlation was detected in five dimensions (p < 0.05).
CONCLUSION
The SF-36 reflects the reduced health status of patients with epistaxis due to HHT. Changes in the SF-36 score could be used as an outcome measure in assessing efficacy of treatment of this condition.
背景
本研究评估经过验证的健康状况调查问卷简式36项健康调查（SF - 36）测量遗传性出血性毛细血管扩张症（HHT）所致鼻出血患者健康状况的能力。
方法
38名患者完成了SF - 36和症状特异性问卷。他们被要求将自己的鼻出血程度评为重度、中度或轻度。将SF - 36数据与参考人群进行比较，并按亚组进行分析。
结果
与参考人群相比，除疼痛外，所有健康维度的得分均显著降低（p < 0.05）。与患者对严重程度的评分相比，在五个维度中检测到显著相关性（p < 0.05）。
结论
SF - 36反映了HHT所致鼻出血患者健康状况的下降。SF - 36评分的变化可作为评估该疾病治疗效果的一项结局指标。
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