Yeates Keith Owen, Taylor H Gerry
Columbus Children's Research Institute, Department of Pediatrics, Ohio State University, OH, USA.
Pediatr Rehabil. 2005 Jan-Mar;8(1):5-16. doi: 10.1080/13638490400011199.
The vast majority of closed-head injuries (CHI) in children are of mild severity. Even if only a small proportion of children with mild CHI suffer persistent negative outcomes, then mild CHI is a serious public health problem. This paper summarizes the existing literature regarding the neurobehavioural outcomes associated with mild CHI in children and adolescents, focusing on the longstanding debate regarding post-concussive syndrome. The paper also discusses conceptual and methodological issues that arise in research on the outcomes of mild CHI, including the definition of mild CHI; selection of comparison groups; measurement of outcomes; assessment of risk factors; timing of outcome assessments; and prediction of outcomes for individual children. The paper describes an ongoing research project that may help to resolve some of the longstanding controversies and uncertainties regarding the outcomes of mild CHI in children and concludes with a review of likely future directions for research on the outcomes of mild CHI. The long-term goal of research in this area is to develop a comprehensive and integrated biopsychosocial model of outcomes that can help guide clinical management.
儿童中绝大多数闭合性颅脑损伤（CHI）为轻度。即便只有一小部分轻度CHI儿童会出现持续的不良后果，轻度CHI仍是一个严重的公共卫生问题。本文总结了关于儿童和青少年轻度CHI相关神经行为后果的现有文献，重点关注关于脑震荡后综合征的长期争论。本文还讨论了轻度CHI后果研究中出现的概念和方法问题，包括轻度CHI的定义；对照组的选择；后果的测量；风险因素的评估；后果评估的时间；以及个体儿童后果的预测。本文描述了一个正在进行的研究项目，该项目可能有助于解决一些关于儿童轻度CHI后果的长期争议和不确定性，并以对轻度CHI后果研究未来可能方向的综述作为结尾。该领域研究的长期目标是建立一个全面综合的生物心理社会后果模型，以帮助指导临床管理。
