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1型糖尿病女性饮食失调的识别与治疗

Identification and treatment of eating disorders in women with type 1 diabetes mellitus.

作者信息

Goebel-Fabbri Ann E, Fikkan Janna, Connell Alexa, Vangsness Laura, Anderson Barbara J

机构信息

Behavioral and Mental Health Unit, Harvard Medical School, Joslin Diabetes Center, Boston, Massachusetts 02215, USA.

出版信息

Treat Endocrinol. 2002;1(3):155-62. doi: 10.2165/00024677-200201030-00003.

Abstract

A series of case reports in the early 1980s and prevalence studies in the 1990s highlighted the serious medical consequences of coexisting eating disorders and diabetes mellitus. Diabetes-specific treatment issues, such as the need to carefully monitor diet, exercise, and blood glucose, may contribute to the development of eating disorder symptoms among women with diabetes mellitus. The attention to food portions and bodyweight that is part of routine diabetes mellitus management parallels the rigid thinking about food and body image found in women with eating disorders who do not have diabetes mellitus. Additionally, intensive insulin management of diabetes mellitus, the current standard of care, has been shown to be associated with bodyweight gain. Following from this, it may be that the very goals of state-of-the-art diabetes mellitus care increase the risk for developing an eating disorder. Once an eating disorder and recurrent insulin omission becomes entrenched, a pattern develops which is hard to break - one of chronic hyperglycemia, depressed mood, fear of bodyweight gain, and frustration with diabetes management. Eating disorders predispose women with diabetes mellitus to many complex medical risks. For example, insulin omission and reduction, eating disorder symptoms unique to diabetes mellitus, are strongly associated with an increased risk of diabetic ketoacidosis and with microvascular complications of diabetes mellitus such as retinopathy. For this reason, it is critical that diabetes mellitus clinicians understand more about eating disorders so as to improve the likelihood of early detection, appropriate treatment, and prevention of acute and long-term medical complications within this high-risk group of women.

摘要

20世纪80年代初的一系列病例报告以及90年代的患病率研究凸显了进食障碍与糖尿病并存所带来的严重医学后果。糖尿病的特异性治疗问题,比如需要仔细监测饮食、运动和血糖,可能会促使糖尿病女性出现进食障碍症状。糖尿病日常管理中对食物分量和体重的关注,与非糖尿病进食障碍女性中存在的对食物和身体形象的刻板思维相似。此外,目前糖尿病的标准治疗方式——强化胰岛素治疗,已被证明与体重增加有关。由此可见,最先进的糖尿病护理目标本身可能会增加患进食障碍的风险。一旦进食障碍和反复漏用胰岛素的情况根深蒂固,就会形成一种难以打破的模式——慢性高血糖、情绪低落、害怕体重增加以及对糖尿病管理感到沮丧。进食障碍使糖尿病女性易面临许多复杂的医学风险。例如,漏用和减少胰岛素这种糖尿病特有的进食障碍症状,与糖尿病酮症酸中毒风险增加以及糖尿病微血管并发症(如视网膜病变)密切相关。因此,糖尿病临床医生更深入了解进食障碍至关重要,以便提高在这一高危女性群体中早期发现、恰当治疗以及预防急性和长期医学并发症的可能性。

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