Schneider Ulrike, Gelisken Faik, Inhoffen Werner
University Eye Clinic Tübingen, Tübingen, Germany.
Acta Ophthalmol Scand. 2005 Apr;83(2):141-7. doi: 10.1111/j.1600-0420.2005.00443.x.
To analyse the frequency of conversion from occult with no classic choroidal neovascularization (CNV) and occult with minimally classic CNV into predominantly classic CNV secondary to age-related macular degeneration.
Retrospective evaluation of baseline and repeat angiograms of 54 eyes with a follow-up of 6-12 months.
In the group with initially occult with no classic CNV, nine of 40 eyes (23%) progressed to a predominantly classic lesion, whereas in the group of occult with a minimally classic CNV, 10 of 14 eyes (71%) eyes developed a predominantly classic CNV.
The proportion of eyes that develop predominantly classic CNV is much higher in eyes with initially occult and minimally classic CNV, compared with eyes with initially occult and no classic CNV. Our data suggest that the natural course of CNV secondary to AMD begins as occult and progresses to classic CNV.
分析年龄相关性黄斑变性继发的隐匿性无典型脉络膜新生血管（CNV）以及隐匿性伴微小典型CNV转变为主要为典型CNV的频率。
对54只眼的基线和重复血管造影进行回顾性评估，随访6 - 12个月。
在最初为隐匿性无典型CNV的组中，40只眼中有9只（23%）进展为主要为典型病变，而在隐匿性伴微小典型CNV的组中，14只眼中有10只（71%）发展为主要为典型CNV。
与最初隐匿性无典型CNV的眼相比，最初隐匿性伴微小典型CNV的眼中发展为主要为典型CNV的比例要高得多。我们的数据表明，年龄相关性黄斑变性继发的CNV自然病程始于隐匿性，并进展为典型CNV。
