Martini Giorgia, Calabrese Fiorella, Biscaro Francesca, Zulian Francesco
Department of Pediatrics, Pathology Institute, University of Padua, Padua, Italy.
J Rheumatol. 2005 Apr;32(4):744-6.
Dermatomyositis (DM) in adults is frequently associated with cancer. In contrast, juvenile DM (JDM) is predominantly idiopathic and rarely reported with occult neoplasm. We describe a patient who presented with DM that was found to be a paraneoplastic manifestation of nasopharyngeal carcinoma. Although rare, paraneoplastic JDM must be suspected in the presence of unusual features such as elevated inflammatory markers or lymphadenopathy. Accurate clinical assessment including appropriate biopsies is needed before starting glucocorticoid therapy.
成人皮肌炎（DM）常与癌症相关。相比之下，青少年皮肌炎（JDM）主要为特发性，很少有隐匿性肿瘤的报道。我们描述了一名表现为皮肌炎的患者，该皮肌炎被发现是鼻咽癌的副肿瘤表现。尽管罕见，但在出现炎症标志物升高或淋巴结病等不寻常特征时，必须怀疑副肿瘤性JDM。在开始糖皮质激素治疗前，需要进行包括适当活检在内的准确临床评估。
