Romero Ortiz Ana, López-Beltrán Antonio, Pérez Luque Alfonso, Requena Tapia María José
Servicio de Anatomía Patológica, Hospital General Universitario Reina Sofía, Córdoba, España.
Arch Esp Urol. 2005 Jan-Feb;58(1):9-16. doi: 10.4321/s0004-06142005000100003.
The article focuses on the multilocular cystic renal carcinoma, the most frequent of the renal cystic carcinomas. The importance of performing a separate analysis of these cystic tumors comes from their better prognosis some authors have suggested. Moreover, they are frequently difficult to differentiate from multilocular benign cysts and other benign lesions by radiological studies, cytology or even during surgery. Pathologic study is essential for a definitive diagnosis of the lesion.
We reviewed 14 cases of multilocular cystic renal carcinoma obtained from the series of 191 renal cell carcinomas diagnosed in our hospital in the period 1995-2002. Inclusion criteria were existence of a multicystic complex mass, in which clear cells partially or completely covered the cystic walls and accumulate within the septa.
The lack of well-documented cases of multilocular cystic renal carcinoma with metastases supports the fact that they are tumors with a very good prognosis. In conclusion, data from both literature and our series support that multilocular cystic renal carcinoma should be considered a low-grade neoplasia, and its treatment should be conservative.
本文聚焦于多房性囊性肾细胞癌,这是肾囊性癌中最常见的类型。对这些囊性肿瘤进行单独分析的重要性在于,一些作者认为它们预后较好。此外,通过影像学研究、细胞学检查甚至在手术过程中,它们常常难以与多房性良性囊肿及其他良性病变相鉴别。病理研究对于明确病变诊断至关重要。
我们回顾了1995年至2002年期间我院诊断的191例肾细胞癌系列中14例多房性囊性肾细胞癌病例。纳入标准为存在多囊性复合肿块,其中透明细胞部分或完全覆盖囊壁并在间隔内积聚。
缺乏多房性囊性肾细胞癌伴转移的充分记录病例,这支持了它们是预后非常好的肿瘤这一事实。总之,文献数据和我们的系列研究均支持多房性囊性肾细胞癌应被视为低级别肿瘤,其治疗应保守。