Raeside J I, Liptrap R M, McDonell W N, Milne F J
J Reprod Fertil Suppl. 1979(27):493-7.
Plasma levels of total oestrogens and dehydroepiandrosterone (DHA) were measured by radioimmunossay in samples taken from various blood vessels in both maternal and fetal compartments in 11 Pony mates. High concentrations of oestrogens (greater than 100 ng/ml of plasma), expressed as oestrone equivalents, were found in the fetal circulation. On both the fetal and maternal sides, oestrogen concentrations were lower in blood going to than from the placenta. DHA concentrations, on the other hand, were higher in blood flowing to the placenta from the fetus. The fetal gonads were seen as the source of DHA, which was present in remarkably high concentrations (greater than 800 ng/ml of plasma) in venous samples from fetal ovaries and fetal testes. A precursor role in placental oestrogen formation is suggested for DHA secretion by the fetal gonads.
通过放射免疫测定法，对11匹母马母体和胎儿各血管采集的样本进行检测，以测定血浆中总雌激素和脱氢表雄酮（DHA）的水平。以雌酮当量表示，在胎儿循环中发现了高浓度的雌激素（血浆中大于100 ng/ml）。在胎儿和母体两侧，流向胎盘的血液中雌激素浓度低于从胎盘流出的血液。另一方面，从胎儿流向胎盘的血液中DHA浓度较高。胎儿性腺被视为DHA的来源，在来自胎儿卵巢和胎儿睾丸的静脉样本中，DHA浓度极高（血浆中大于800 ng/ml）。提示胎儿性腺分泌的DHA在胎盘雌激素形成中起前体作用。
