Seçil Yaprak, Ozdedeli Kaan, Altay Bariş, Aydoğdu Ibrahim, Yilmaz Candeğer, Ertekin Cumhur
Atatürk Education and Research Hospital, Neurology Department, Oyak Sitesi 2/3 sok. B-9 Blok, No : 9/11 35350 Uçkuyular, Izmir, Turkey; Ege University Medical School Hospital, Department of Clinical Neurophysiology, Izmir, Turkey.
Neurophysiol Clin. 2005 Feb;35(1):11-7. doi: 10.1016/j.neucli.2004.12.001. Epub 2005 Jan 21.
An electrophysiological technique assessing the sympathetic skin activity related to sudomotor function from the genital skin has been described previously in normal adult man. The problems of the genitourinary tracts and the sexual disorders are difficult to analyse in women. In this paper, a method for recording the genital sympathetic skin responses (g-SSR) has been described in normal women and the objective changes were demonstrated in female patients with diabetes mellitus.
Our study comprised 20 healthy adult women (mean age 42.5 years) and 20 diabetic women (mean age 52.8 years). We examined both left hand sympathetic skin responses (SSR) and genital region SSR by electrophysiological methods. Superficial Ag-AgCl electrodes were placed on perineum in front of the anal sphincter and 1-1.5 cm lateral to right labia majora for recording after the stimulation of the right median nerve. All g-SSRs from both recording sites were analysed, latency and amplitudes were compared in normal subjects and patients.
It has been clearly demonstrated that the g-SSR is easily obtained from all normal female subjects in labia majora-perineum montage. In seven of 20 diabetic patients g-SSR could not be elicited. Mean amplitude was significantly reduced in diabetic group according to normal subjects (P < 0.05).
It was concluded that the method described in this study is easily applied and objectively evaluated for the female patients with genitourinary and sexual problems.
先前已描述了一种评估正常成年男性生殖器皮肤与汗腺运动功能相关的交感神经皮肤活动的电生理技术。女性的泌尿生殖道问题和性功能障碍很难分析。本文描述了一种记录正常女性生殖器交感神经皮肤反应(g-SSR)的方法,并在糖尿病女性患者中证明了客观变化。
我们的研究包括20名健康成年女性(平均年龄42.5岁)和20名糖尿病女性(平均年龄52.8岁)。我们通过电生理方法检查了左手交感神经皮肤反应(SSR)和生殖器区域SSR。将表面Ag-AgCl电极置于肛门括约肌前方的会阴以及右大阴唇外侧1-1.5厘米处,用于在刺激右正中神经后进行记录。分析了两个记录部位的所有g-SSR,比较了正常受试者和患者的潜伏期和振幅。
已清楚表明,在大阴唇-会阴组合中,所有正常女性受试者都很容易获得g-SSR。20名糖尿病患者中有7名无法引出g-SSR。与正常受试者相比,糖尿病组的平均振幅显著降低(P < 0.05)。
得出的结论是,本研究中描述的方法易于应用,并且可以对患有泌尿生殖和性问题的女性患者进行客观评估。