Remadi S, Korbi S, Kuffer R
Département de Pathologie, Centre Médical Universitaire, CH-1211, Genève, Suisse.
Ann Pathol. 1992;12(1):29-33.
A 73 year-old man consulted for a swelling of the endentulous horizontal branch of the mandible. X-ray examination showed a lytic defect. Two successive, but superficial biopsies, directed the diagnosis towards osteomyelitis. In spite of antibiotic therapy, the destruction continued to progress and was finally complicated by a pathological fracture. A radial resection of the horizontal branch of the mandible was performed; on this surgical specimen the diagnosis of primitive lymphoma of the mandible (diffuse centroblastic type) was made. The authors discuss the diagnostic difficulties of mandibular lymphomas, which according to Ostrowski represent 4.7 per cent of the primitive bone lymphoma.
一名73岁男性因下颌无牙水平支肿胀前来就诊。X线检查显示有溶骨性缺损。连续两次进行的表浅活检，使诊断倾向于骨髓炎。尽管进行了抗生素治疗，骨质破坏仍在进展，最终并发病理性骨折。遂对下颌水平支进行了桡骨切除术；在该手术标本上确诊为下颌原发性淋巴瘤（弥漫性中心母细胞型）。作者讨论了下颌淋巴瘤的诊断困难，根据奥斯特罗夫斯基的研究，下颌淋巴瘤占原发性骨淋巴瘤的4.7%。
