Robbins K T, Fuller L M, Manning J, Goepfert H, Velasquez W S, Sullivan M P, Finkelstein J B
Head Neck Surg. 1986 Jan-Feb;8(3):192-9. doi: 10.1002/hed.2890080311.
The mandible is an uncommon presentation site for lymphoma and misdiagnosis is common. Eleven patients with lymphoma of the mandible were seen between 1947 and 1983. In 5 of the 11 patients, the diagnosis of lymphoma could not be established from the initial biopsy and additional material for examination was required. In three patients, this resulted in a partial or total removal of the mandible. In a recent histopathologic review, the diagnosis of diffuse large cell was made in seven, diffuse undifferentiated (non-Burkitt's) in two, diffuse undifferentiated (Burkitt's) in one, and unclassified in one. Using the Ann Arbor method of staging, six patients were determined to have stage IE disease; three had stage IIE, and two had stage IV. In 10 patients definitive treatment consisted of radiotherapy, chemotherapy, or a combination of both. Treatment was limited to surgery in one patient. The 5-year overall and disease-free survival rates were 62% and 50%, respectively. These results are comparable to those for lymphoma of other extranodal head and neck sites.
下颌骨是淋巴瘤少见的发病部位，误诊很常见。1947年至1983年间共诊治了11例下颌骨淋巴瘤患者。11例患者中有5例最初活检无法确诊淋巴瘤，需要更多检查材料。其中3例患者因此接受了下颌骨部分或全部切除。在最近的组织病理学复查中，7例诊断为弥漫大细胞型，2例为弥漫未分化型（非伯基特型），1例为弥漫未分化型（伯基特型），1例未分类。采用安阿伯分期法，6例患者为IE期，3例为IIE期，2例为IV期。10例患者的确定性治疗包括放疗、化疗或两者联合。1例患者仅接受了手术治疗。5年总生存率和无病生存率分别为62%和50%。这些结果与其他头颈部结外淋巴瘤部位的结果相当。
