Suppr超能文献

使用最小数据集的初次动脉手术后死亡率的风险调整预测模型。

Risk-adjusted predictive models of mortality after index arterial operations using a minimal data set.

作者信息

Prytherch D R, Ridler B M F, Ashley S

机构信息

Department of Information Systems and Computer Applications, University of Portsmouth, UK.

出版信息

Br J Surg. 2005 Jun;92(6):714-8. doi: 10.1002/bjs.4965.

Abstract

BACKGROUND

Reducing the data required for a national vascular database (NVD) without compromising the statistical basis of comparative audit is an important goal. This work attempted to model outcomes (mortality and morbidity) from a small and simple subset of the NVD data items, specifically urea, sodium, potassium, haemoglobin, white cell count, age and mode of admission.

METHODS

Logistic regression models of risk of adverse outcome were built from the 2001 submission to the NVD using all records that contained the complete data required by the models. These models were applied prospectively against the equivalent data from the 2002 submission to the NVD.

RESULTS

As had previously been found using the P-POSSUM (Portsmouth POSSUM) approach, although elective abdominal aortic aneurysm (AAA) repair and infrainguinal bypass (IIB) operations could be described by the same model, separate models were required for carotid endarterectomy (CEA) and emergency AAA repair. For CEA there were insufficient adverse events recorded to allow prospective testing of the models. The overall mean predicted risk of death in 530 patients undergoing elective AAA repair or IIB operations was 5.6 per cent, predicting 30 deaths. There were 28 reported deaths (chi(2) = 2.75, 4 d.f., P = 0.600; no evidence of lack of fit). Similarly, accurate predictions were obtained across a range of predicted risks as well as for patients undergoing repair of ruptured AAA and for morbidity.

CONCLUSION

A 'data economic' model for risk stratification of national data is feasible. The ability to use a minimal data set may facilitate the process of comparative audit within the NVD.

摘要

背景

在不影响比较性审计统计基础的前提下,减少国家血管数据库(NVD)所需的数据是一个重要目标。这项工作试图从NVD数据项的一个小而简单的子集中对结果(死亡率和发病率)进行建模,具体包括尿素、钠、钾、血红蛋白、白细胞计数、年龄和入院方式。

方法

利用2001年提交给NVD的所有包含模型所需完整数据的记录,建立不良结局风险的逻辑回归模型。这些模型被前瞻性地应用于2002年提交给NVD的等效数据。

结果

正如之前使用P-POSSUM(朴茨茅斯手术严重性评估系统)方法所发现的那样,虽然择期腹主动脉瘤(AAA)修复和股动脉以下旁路移植术(IIB)手术可以用同一个模型描述,但颈动脉内膜切除术(CEA)和急诊AAA修复需要单独的模型。对于CEA,记录的不良事件不足,无法对模型进行前瞻性测试。530例接受择期AAA修复或IIB手术的患者总体平均预测死亡风险为5.6%,预测死亡30例。报告死亡28例(χ² = 2.75,自由度为4,P = 0.600;无拟合不足的证据)。同样,在一系列预测风险中,以及对于接受破裂AAA修复的患者和发病率,都获得了准确的预测。

结论

一种用于国家数据风险分层的“数据经济”模型是可行的。使用最小数据集的能力可能会促进NVD内的比较性审计过程。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验