Rodighiero D, Fusato G, Vidali M, Zuccarotto D, Gaspari L
Divisione di Chirurgia Generale II, Ospedale Civile di Vicenza.
G Chir. 1992 Mar;13(3):92-4.
The study was carried out on 100 patients over 70 suffering from rectal cancer. The operative death-rate resulted higher in wider resections than in more limited ones, though the former showed a lower incidence of relapse and higher survival rates. Operative death-rate was more strictly related to the presence of cardiorespiratory alterations than to age per se. As a consequence, in Authors' opinion, surgical therapy is not to be completely rejected in old-aged patients; on the contrary it should be discussed according to the patient status. With the increase of the population mean age rectal cancer diagnosis in old patients has become more frequent; nowadays, improvements in anaesthesia and reanimation practice allow a considerable decrease in surgical risks with a corresponding increased possibility of a radical surgical therapy.
该研究针对100名70岁以上的直肠癌患者开展。虽然广泛切除术后复发率较低且生存率较高，但广泛切除术的手术死亡率高于有限切除术。手术死亡率与心肺功能改变的相关性比与年龄本身的相关性更强。因此，作者认为，老年患者不应完全拒绝手术治疗；相反，应根据患者的具体情况进行讨论。随着人口平均年龄的增加，老年患者直肠癌的诊断变得更加频繁；如今，麻醉和复苏技术的进步使得手术风险大幅降低，根治性手术治疗的可能性相应增加。
