Yoon Grace, Beischel Linda S, Johnson John P, Jones Marilyn C
Department of Pediatrics, Division of Medical Genetics, University of California-San Francisco, San Francisco, CA, USA.
J Pediatr. 2005 Apr;146(4):565-7. doi: 10.1016/j.jpeds.2004.12.021.
Assisted reproductive technology (ART) has now become a cornerstone of treatment for involuntary infertility. Recent studies have raised concern regarding potential associations between ART and chromosomal aneuploidy, imprinting anomalies, and monochorionic placentation in dizygotic (DZ) twins. We report a case of DZ twins conceived by ART in which all three problems coexist.
辅助生殖技术(ART)现已成为治疗非自愿性不孕的基石。最近的研究引发了人们对ART与染色体非整倍体、印记异常以及双合子(DZ)双胞胎的单绒毛膜胎盘形成之间潜在关联的关注。我们报告了一例通过ART受孕的DZ双胞胎病例,其中这三个问题同时存在。