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通过辅助生殖技术受孕的双卵双胎妊娠与染色体异常、印记障碍和单绒毛膜胎盘形成有关。

Dizygotic twin pregnancy conceived with assisted reproductive technology associated with chromosomal anomaly, imprinting disorder, and monochorionic placentation.

作者信息

Yoon Grace, Beischel Linda S, Johnson John P, Jones Marilyn C

机构信息

Department of Pediatrics, Division of Medical Genetics, University of California-San Francisco, San Francisco, CA, USA.

出版信息

J Pediatr. 2005 Apr;146(4):565-7. doi: 10.1016/j.jpeds.2004.12.021.

DOI:10.1016/j.jpeds.2004.12.021
PMID:15812468
Abstract

Assisted reproductive technology (ART) has now become a cornerstone of treatment for involuntary infertility. Recent studies have raised concern regarding potential associations between ART and chromosomal aneuploidy, imprinting anomalies, and monochorionic placentation in dizygotic (DZ) twins. We report a case of DZ twins conceived by ART in which all three problems coexist.

摘要

辅助生殖技术(ART)现已成为治疗非自愿性不孕的基石。最近的研究引发了人们对ART与染色体非整倍体、印记异常以及双合子(DZ)双胞胎的单绒毛膜胎盘形成之间潜在关联的关注。我们报告了一例通过ART受孕的DZ双胞胎病例,其中这三个问题同时存在。

相似文献

1
Dizygotic twin pregnancy conceived with assisted reproductive technology associated with chromosomal anomaly, imprinting disorder, and monochorionic placentation.通过辅助生殖技术受孕的双卵双胎妊娠与染色体异常、印记障碍和单绒毛膜胎盘形成有关。
J Pediatr. 2005 Apr;146(4):565-7. doi: 10.1016/j.jpeds.2004.12.021.
2
Genomic imprinting and assisted reproductive technology: connections and potential risks.基因组印记与辅助生殖技术:联系及潜在风险
Semin Reprod Med. 2005 Aug;23(3):285-95. doi: 10.1055/s-2005-872457.
3
Are children born after assisted reproductive technology at increased risk for adverse health outcomes?通过辅助生殖技术出生的儿童出现不良健康结局的风险会增加吗?
Obstet Gynecol. 2004 Jun;103(6):1154-63. doi: 10.1097/01.AOG.0000124571.04890.67.
4
Imprinting and assisted reproductive technology.印记与辅助生殖技术。
Hum Mol Genet. 2005 Apr 15;14 Spec No 1:R133-8. doi: 10.1093/hmg/ddi107.
5
Umbilical cord anomalies are more frequent in twins after assisted reproduction.辅助生殖后的双胞胎中,脐带异常更为常见。
Hum Reprod. 2007 Oct;22(10):2763-7. doi: 10.1093/humrep/dem191. Epub 2007 Aug 24.
6
Assisted reproduction technology and defects of genomic imprinting.辅助生殖技术与基因组印记缺陷
BJOG. 2005 Dec;112(12):1589-94. doi: 10.1111/j.1471-0528.2005.00784.x.
7
Assisted reproductive technologies and birth defects.辅助生殖技术与出生缺陷。
Congenit Anom (Kyoto). 2005 Jun;45(2):39-43. doi: 10.1111/j.1741-4520.2005.00061.x.
8
Evidence for blood chimerism in dizygotic spontaneous twin pregnancy discordant for Down syndrome.唐氏综合征不一致的双卵自然双胎妊娠中血液嵌合体的证据。
Prenat Diagn. 2006 Sep;26(9):782-4. doi: 10.1002/pd.1503.
9
Naturally conceived twins with monochorionic placentation have the highest risk of fetal loss.自然受孕的单绒毛膜胎盘双胎胎儿丢失风险最高。
Ultrasound Obstet Gynecol. 2006 Oct;28(5):644-52. doi: 10.1002/uog.3820.
10
[Epigenetic perspectives of safety in assisted reproductive technologies].[辅助生殖技术安全性的表观遗传学视角]
Genetika. 2007 Sep;43(9):1157-71.

引用本文的文献

1
The risk of malformation following assisted reproduction.辅助生殖后的畸形风险。
Dtsch Arztebl Int. 2008 Jan;105(1-2):11-7. doi: 10.3238/arztebl.2008.0011. Epub 2008 Jan 7.
2
Traces of embryogenesis are the same in monozygotic and dizygotic twins: not compatible with double ovulation.单卵双胞胎和双卵双胞胎的胚胎发育痕迹是相同的:与双排卵不相符。
Hum Reprod. 2009 Jun;24(6):1255-66. doi: 10.1093/humrep/dep030. Epub 2009 Feb 27.