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酒精性肝病患者的肝移植

Liver transplantation in alcoholic patients.

作者信息

Burra Patrizia, Lucey Michael R

机构信息

Section of Gastroenterology, Liver Gastroenterology Transplantation, Department of Surgical and Gastroenterological Sciences, University Hospital, University of the Study, Padua, Italy.

出版信息

Transpl Int. 2005 May;18(5):491-8. doi: 10.1111/j.1432-2277.2005.00079.x.

Abstract

Alcoholic liver disease is one of the most common causes of cirrhosis and indications for orthotopic liver transplantation in Europe and North America. The reluctance to transplant alcoholics stems in part from the view that alcoholics bear responsibility for their illness. There is also the perception that the alcoholic person is likely to relapse into alcohol use after transplantation and thereby damage the allograft. In this review, we considered the evaluation for and outcome of liver transplantation in alcoholics with special attention to the specific risks of alcohol relapse, to show that alcoholism should be considered like other co-morbid states rather than as a moral flaw.

摘要

酒精性肝病是欧洲和北美的肝硬化以及原位肝移植指征的最常见病因之一。不愿为酗酒者进行肝移植,部分原因是认为酗酒者应对自己的疾病负责。还有一种看法是,酗酒者在移植后很可能重新开始饮酒,从而损害移植的肝脏。在这篇综述中,我们考虑了酗酒者肝移植的评估及预后情况,特别关注了酒精复饮的具体风险,以表明酗酒应像其他共病状态一样看待,而不应被视为一种道德缺陷。

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