Conde-Agudelo A, Belizán J M, Breman R, Brockman S C, Rosas-Bermudez A
Latin American Center for Perinatology and Human Development, Division of Health Promotion and Protection, Pan American Health Organization, World Health Organization, Montevideo, Uruguay.
Int J Gynaecol Obstet. 2005 Apr;89 Suppl 1:S34-40. doi: 10.1016/j.ijgo.2004.08.003.
To investigate whether the length of the interval between an abortion and the next pregnancy is associated with increased risks of adverse maternal and perinatal outcomes in Latin America.
Retrospective cross-sectional study using information from 258,108 women delivering singleton infants and whose previous pregnancy resulted in abortion recorded in the Perinatal Information System database of the Latin American Centre for Perinatology and Human Development, Montevideo, Uruguay, between 1985 and 2002. Adjusted odds ratios were obtained through logistic regression analysis.
Compared with the post-abortion interpregnancy intervals of 18 to 23 months, intervals shorter than 6 months were significantly associated with increased risks of maternal anemia, premature rupture of membranes, low birth weight, very low birth weight, preterm delivery, and very preterm delivery.
In Latin America, post-abortion interpregnancy intervals shorter than 6 months are independently associated with increased risks of adverse maternal and perinatal outcomes in the next pregnancy.
Post-abortion interpregnancy interval (PAII): the time elapsed between the day of the abortion and the first day of the last menstrual period for the index pregnancy.
调查拉丁美洲地区人工流产与下次怀孕之间的间隔时间长短是否与孕产妇和围产期不良结局风险增加有关。
采用回顾性横断面研究，利用1985年至2002年期间乌拉圭蒙得维的亚拉丁美洲围产医学与人类发展中心围产信息系统数据库中记录的258,108例分娩单胎婴儿且上次怀孕为人工流产的妇女的信息。通过逻辑回归分析获得调整后的比值比。
与人工流产后18至23个月的妊娠间隔相比，短于6个月的间隔与孕产妇贫血、胎膜早破、低出生体重、极低出生体重、早产和极早产风险增加显著相关。
在拉丁美洲，人工流产后妊娠间隔短于6个月与下次怀孕时孕产妇和围产期不良结局风险增加独立相关。
人工流产后妊娠间隔（PAII）：人工流产之日与本次妊娠末次月经首日之间的时间间隔。
