Fuller Trevon, Sarkar Sahotra, Crews David
Section of Integrative Biology, University of Texas at Austin, Austin, TX 78712, USA.
Neurosci Biobehav Rev. 2005 May;29(3):445-56. doi: 10.1016/j.neubiorev.2004.12.005.
Norms of reaction (NoRs) represent the phenotypic values of genotypes as functions of environmental parameters and permit the visualization of differences in phenotypic response of different genotypes. NoR graphs can be used to analyze interactions between genotypic and environmental factors during development to produce phenotypes in inbred strains of rats and mice. We describe the main features of NoRs, the history of their use in this context, and discuss several applications in behavioral neuroscience. In addition, we give a test for determining whether distinct strains have different NoRs.
反应规范（NoRs）表示基因型的表型值是环境参数的函数，并允许直观呈现不同基因型表型反应的差异。反应规范图可用于分析大鼠和小鼠近交系在发育过程中基因型和环境因素之间的相互作用，以产生表型。我们描述了反应规范的主要特征、在这种情况下其使用的历史，并讨论了行为神经科学中的几个应用。此外，我们给出了一种用于确定不同品系是否具有不同反应规范的测试方法。
