Romano P S, Mark D H
Institute for Health Policy Studies University of California, San Francisco.
Chest. 1992 May;101(5):1332-7. doi: 10.1378/chest.101.5.1332.
Several recent reports from academic centers have documented very low postoperative mortality after lung cancer surgery. However, generalizing these studies to community hospitals is potentially limited by reporting bias. From California hospital discharge abstracts, we identified 12,439 adults who underwent pulmonary resection for lung or bronchial tumors between January 1983 and December 1986. In-hospital mortality was 3.8 percent after wedge resection, 3.7 percent after segmental resection, 4.2 percent after lobectomy, and 11.6 percent after pneumonectomy. In multivariate regression models, the significant predictors of in-hospital death included age 60 years or more, male gender, extended resection, chronic lung or heart disease, diabetes and hospital volume. High-volume hospitals experienced better outcomes than low-volume hospitals, although unmeasured severity of illness may be a confounder. The overall mortality in this community-based sample exceeds that reported by selected centers and provides a better foundation for advising patients.
学术中心最近的几份报告记录了肺癌手术后极低的术后死亡率。然而,将这些研究推广到社区医院可能会受到报告偏倚的限制。从加利福尼亚州医院出院摘要中,我们识别出1983年1月至1986年12月期间接受肺或支气管肿瘤肺切除术的12439名成年人。楔形切除术后住院死亡率为3.8%,肺段切除术后为3.7%,肺叶切除术后为4.2%,全肺切除术后为11.6%。在多变量回归模型中,住院死亡的显著预测因素包括60岁及以上年龄、男性、扩大切除术、慢性肺或心脏病、糖尿病和医院规模。高规模医院比低规模医院有更好的治疗结果,尽管未测量的疾病严重程度可能是一个混杂因素。这个基于社区的样本中的总体死亡率超过了选定中心报告的死亡率,为向患者提供建议提供了更好的依据。