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一名肾衰竭患者的钆脑病

Gadolinium encephalopathy in a patient with renal failure.

作者信息

Maramattom Boby Varkey, Manno Edward M, Wijdicks Eelco F M, Lindell Edward P

机构信息

Division of Critical Care Neurology, Department of Neurology, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.

出版信息

Neurology. 2005 Apr 12;64(7):1276-8. doi: 10.1212/01.WNL.0000156805.45547.6E.

DOI:10.1212/01.WNL.0000156805.45547.6E
PMID:15824364
Abstract

Gadolinium chelates are extensively used in MRI studies. Neurotoxicity due to gadolinium chelates is minimal and uncommon. A 57-year-old woman in renal failure developed a subacute encephalopathy after inadvertent repetitive gadolinium contrast administration. An unusual MRI appearance with CSF hyperintensity due to gadolinium diffusion into the CSF is also shown.

摘要

钆螯合物广泛应用于磁共振成像(MRI)研究。钆螯合物所致的神经毒性极小且不常见。一名57岁的肾衰竭女性在无意中重复使用钆造影剂后出现了亚急性脑病。还展示了一种不寻常的MRI表现,即由于钆扩散到脑脊液中导致脑脊液信号增强。

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