Lee Michael, Ramaswamy Mohan R, Lilien David L, Nathan Cherie-Ann O
Department of Otolaryngology, Louisiana State University-Health Sciences Center, Shreveport, Louisiana 71130-3932, USA.
Ann Otol Rhinol Laryngol. 2005 Mar;114(3):202-6. doi: 10.1177/000348940511400306.
Positron emission tomography (PET) is used in the management of head and neck cancers. It identifies tissue with increased metabolic activity and is not specific for malignancy. A false-positive PET scan of the larynx is associated with vocal cord paralysis. We reviewed PET scan reports of patients with lung cancer from 1998 to 2001 to identify patients with increased 18-fluoro-2-deoxyglucose uptake in the larynx without a known history of head and neck cancer and then correlated this increased uptake with laryngoscopic findings. There were 17 patients who had a positive PET finding in the larynx. Fifteen of those had a false-positive PET scan in the larynx. All had contralateral vocal cord paralysis. Two patients were noted to have head and neck cancer. We conclude that vocal cord paralysis can cause a false-positive PET scan on the contralateral side of the larynx due to overactivity of laryngeal muscles that compensate for the paralyzed cord.
正电子发射断层扫描（PET）用于头颈部癌症的管理。它可识别代谢活性增加的组织，并非特异性针对恶性肿瘤。喉部PET扫描假阳性与声带麻痹有关。我们回顾了1998年至2001年肺癌患者的PET扫描报告，以识别无已知头颈部癌症病史但喉部18-氟-2-脱氧葡萄糖摄取增加的患者，然后将这种摄取增加与喉镜检查结果相关联。有17例患者喉部PET检查呈阳性。其中15例喉部PET扫描为假阳性。所有患者均有对侧声带麻痹。2例患者被发现患有头颈部癌症。我们得出结论，声带麻痹可导致喉部对侧PET扫描出现假阳性，这是由于补偿麻痹声带的喉部肌肉活动过度所致。
