Rossa B
Zahn Mund Kieferheilkd Zentralbl. 1979;67(3):235-41.
This paper describes the results of observation by optical microscopy of the changes in structure of the epithelium of the human oral mucous membrane between birth and old age. The intraepithelial regulatory mechanism of the oral mucous membrane can be disturbed by exogenous and endogenous factors, as a result of which it is possible for the mucosa to lose part of its resistance to external influences. Sex hormones are considered to play an important role in this connection. In the intrauterine state, the epithelium has no stratum corneum. However, a stratum corneum can be seen to develop, in the form of a parakeratosis, already shortly after birth. During puberty, there is observed the capacity to develop, on the palate and gingiva, a protective layer of anuclear horny lumps. At the beginning of the climacteric, the palatal epithelium can be seen to undergo changes in the direction of the prepuberal condition or intermediate stages. The buccal epithelium is invariably free from keratinization and does not usually show such pronounced changes with aging.
本文描述了通过光学显微镜观察人口腔黏膜上皮在出生至老年期间结构变化的结果。口腔黏膜的上皮内调节机制可能会受到外源性和内源性因素的干扰，其结果是黏膜可能会失去部分对外界影响的抵抗力。性激素被认为在这方面起着重要作用。在子宫内状态时，上皮没有角质层。然而，出生后不久就能看到角质层以不全角化的形式开始形成。在青春期，在上腭和牙龈上观察到有能力形成一层由无核角质团块组成的保护层。在更年期开始时，可以看到腭部上皮朝着青春期前状态或中间阶段的方向发生变化。颊部上皮始终无角化，并且通常不会随着年龄增长而出现如此明显的变化。
