Klein-Szanto A J, Schroeder H E
J Anat. 1977 Feb;123(Pt 1):93-109.
The papillary body of the human oral mucosa was studied at six different sites. Biopsy and autopsy material from 57 individuals, 11-81 years of age, was split chemically along the basal lamina and the epithelium-connective tissue interface examined by light and scanning electron microscopy. Morphometric techniques were employed in order to determine: epithelial thickness, height and density of connective tissue papillae and the percentage of basal epithelial surfaces occupied by them. In the majority of sites, connective tissue plateaux or ridges carrying a variable number of single or grouped papillae were found to be the basic structural units of the papillary body. Three regions with diferent characteristics of the epithelium-connective tissue interface could be identified: (1) floor of the mouth, (2) lip and cheek, (3) gingiva and hard palate. The floor of the mouth showed the lowest connective tissue papillae density, the smallest papillae, and connective tissue plateaux separated by narrow grooves. Lip and cheek mucosae revealed an intermediate density, the papillae were frequently bifurcated and angulated. Gingiva and hard palate were characterized by the highest papillary density and by papillae which were cylindrical, slender and erect. The alveolar mucosa exhibited intermediate features between those of the floor of the mouth and those of the cheek mucosa.
在六个不同部位对人类口腔黏膜的乳头体进行了研究。取自57名年龄在11至81岁之间个体的活检和尸检材料，沿着基底层进行化学分离，并通过光学显微镜和扫描电子显微镜检查上皮-结缔组织界面。采用形态计量学技术来确定：上皮厚度、结缔组织乳头的高度和密度以及它们占据的基底上皮表面的百分比。在大多数部位，发现携带不同数量单个或成群乳头的结缔组织平台或嵴是乳头体的基本结构单位。可以识别出上皮-结缔组织界面具有不同特征的三个区域：(1) 口底，(2) 唇和颊，(3) 牙龈和硬腭。口底显示出最低的结缔组织乳头密度、最小的乳头以及由狭窄凹槽分隔的结缔组织平台。唇和颊黏膜显示出中等密度，乳头经常分叉且有角度。牙龈和硬腭的特征是乳头密度最高，乳头呈圆柱形、细长且直立。牙槽黏膜表现出口底黏膜和颊黏膜之间的中间特征。
