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与多种自身免疫性疾病相关的骨髓增生异常综合征

Myelodysplastic syndrome associated with multiple autoimmune disorders.

作者信息

Farmakis Dimitrios, Polymeropoulos Evaggelos, Polonifi Aikaterini, Deftereos Spyros, Giakoumi Xanthoula, Floudas Harris, Grapsa Antonia, Aessopos Athanasios

机构信息

First Department of Internal Medicine, Laiko General Hospital, University of Athens Medical School, Greece.

出版信息

Clin Rheumatol. 2005 Aug;24(4):428-30. doi: 10.1007/s10067-004-1059-4. Epub 2005 Apr 13.

DOI:10.1007/s10067-004-1059-4
PMID:15827686
Abstract

The association between myelodysplastic syndromes (MDS) and autoimmune manifestations is not uncommon. As a rule, autoimmune abnormalities follow the diagnosis of MDS. We describe here a patient with MDS who developed a striking spectrum of diverse autoimmune disorders, including dermatitis, polyarthritis, and vasculitis, which preceded the clinical appearance of MDS.

摘要

骨髓增生异常综合征(MDS)与自身免疫表现之间的关联并不罕见。通常,自身免疫异常在MDS诊断之后出现。我们在此描述一名MDS患者,该患者在MDS临床表现出现之前就出现了一系列显著的、多样的自身免疫性疾病,包括皮炎、多关节炎和血管炎。

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本文引用的文献

1
Autoimmune phenomena in myelodysplastic syndromes: a 4-yr prospective study.骨髓增生异常综合征中的自身免疫现象:一项4年的前瞻性研究。
Rheumatology (Oxford). 2004 May;43(5):626-32. doi: 10.1093/rheumatology/keh136. Epub 2004 Feb 24.
2
Myelodysplastic syndromes.骨髓增生异常综合征
Hematol J. 2004;5(1):1-8. doi: 10.1038/sj.thj.6200335.
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The myelodysplastic syndromes: a matter of life or death.骨髓增生异常综合征:生死攸关之事。
Acta Haematol. 2004;111(1-2):78-99. doi: 10.1159/000074488.
4
Rheumatoid-like polyarthritis as a presenting feature of metastatic carcinoma: a case presentation and review of the literature.类风湿样多关节炎作为转移性癌的首发特征:1例病例报告及文献复习
Clin Rheumatol. 2003 Oct;22(4-5):353-4. doi: 10.1007/s10067-003-0741-2.
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Hematopoietic growth factors in myelodysplastic syndromes.骨髓增生异常综合征中的造血生长因子
Curr Hematol Rep. 2003 Nov;2(6):453-8.
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Evidence for expression of early myeloid antigens in mature, non-blast myeloid cells in myelodysplasia.骨髓增生异常综合征中成熟非原始髓系细胞表达早期髓系抗原的证据。
Am J Hematol. 2003 Sep;74(1):9-16. doi: 10.1002/ajh.10372.
7
Biological and clinical significance of clonogenic assays in patients with myelodysplastic syndromes.克隆形成试验在骨髓增生异常综合征患者中的生物学及临床意义
Med Oncol. 2002;19(4):249-59. doi: 10.1385/MO:19:4:249.
8
Myelodysplastic syndrome accompanied by Addison's disease and multiple autoimmune phenomena: steroid therapy resolved cytopenias and all immune disorders.骨髓增生异常综合征伴艾迪生病及多种自身免疫现象:类固醇治疗使血细胞减少症及所有免疫紊乱得以缓解。
Intern Med. 2001 Oct;40(10):1041-4. doi: 10.2169/internalmedicine.40.1041.
9
Cancer polyarthritis resembling rheumatoid arthritis as a first sign of hidden neoplasms. Report of two cases and review of the literature.类癌性多关节炎酷似类风湿关节炎作为隐匿性肿瘤的首发症状。两例报告并文献复习。
Scand J Rheumatol. 2001;30(1):40-4. doi: 10.1080/030097401750065319.
10
Myelodysplasia presenting as monoarthritis.以单关节炎形式表现的骨髓发育异常。
J Rheumatol. 1997 Jul;24(7):1446-7.