Ouzounian Sophie, Christin-Maitre Sophie
Service d'endocrinologie de la reproduction, hôpital Saint-Antoine, 75012 Paris.
Rev Prat. 2005 Feb 28;55(4):363-8.
Menopause is a natural phenomenon consisting in follicles atresia and decrease in ovarian hormonal secretions. The mean age of menopause is 51 years. It is known that follicles atresia is partially explained by genetics factors. During this period, we observe hormonal variations. The most important of them are an elevation of FSH level, a decrease in estrogens. We also note a variation of androgens secretion. Hypo-oestrogenia induces various clinical symptoms. Some of them occur early in menopause (climateric syndrom), others occur later (osteoporosis, cardiovascular diseases).
更年期是一种自然现象，表现为卵泡闭锁和卵巢激素分泌减少。更年期的平均年龄为51岁。已知卵泡闭锁部分由遗传因素解释。在此期间，我们观察到激素变化。其中最重要的是促卵泡生成素（FSH）水平升高，雌激素水平降低。我们还注意到雄激素分泌的变化。雌激素缺乏会引发各种临床症状。其中一些在更年期早期出现（更年期综合征），另一些则在后期出现（骨质疏松症、心血管疾病）。
