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绝经年龄作为生殖衰老的一个标志。

Age at menopause as a marker of reproductive ageing.

作者信息

te Velde E R, Dorland M, Broekmans F J

机构信息

Department Fertility and Endocrinology, University Hospital Utrecht, The Netherlands.

出版信息

Maturitas. 1998 Oct 12;30(2):119-25.

PMID:9871906
Abstract

Ages of menopause and of the preceding reproductive events such as the beginning of subfertility and infertility, are likely to be dictated by the process of follicle depletion leading to loss of oocyte quantity and quality. To some extent this process is influenced by lifestyle factors like smoking, and possibly also by the use of oral contraceptives. Genetic factors and possibly also events during intrauterine life, probably play a more important role in the age-dependent decrease of female fertility.

摘要

绝经年龄以及之前的生殖事件,如生育力下降和不孕的起始年龄,可能由卵泡耗竭过程决定,该过程会导致卵母细胞数量和质量的丧失。在一定程度上,这一过程受吸烟等生活方式因素影响,也可能受口服避孕药使用的影响。遗传因素以及子宫内生活期间可能发生的事件,可能在女性生育力随年龄下降过程中发挥更重要的作用。

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