Atilla Huban, Batioğlu Figen, Erkam Necile
Department of Ophthalmology, Ankara University School of Medicine, Ankara, Turkey.
Binocul Vis Strabismus Q. 2005;20(1):33-7.
To determine the changes in retinal nerve fiber layer thickness in subjects with high hyperopia and anisometropic amblyopia.
Retinal nerve fiber layer thickness was measured with scanning laser polarimetry and confocal scanning laser tomography in subjects with hyperopia (n=18) with a mean age of 16.6 +/-3.1 years and anisometropic amblyopia (n=14) with a mean age of 17.4 +/-3.8 years. A control group consisted of 25 healthy emmetropic subjects with a mean age of 25.7 +/-11.8 years. In all subjects 3 measurements with 2 different techniques were obtained and the average values for each parameter were analyzed and compared between the groups.
Heidelberg Retinal Tomography revealed a smaller disc area and cup/disc ratio (C/D) in the hyperopic and amblyopic subjects in comparison to the control group, however there was no statistically significant difference between the hyperopia and amblyopia groups. Increased nerve fiber layer thickness in these groups had no statistical significance. There was also no statistically significant difference in various parameters in the measurements taken with scanning laser polarimetry.
Refractive errors may change the quantitative assessment of optic nerve head topography and retinal nerve fiber layer thickness. There is no associated nerve fiber layer changes in anisometropic amblyopic subjects in comparison to the control group and the subjects with high hyperopia.
确定高度远视和屈光参差性弱视患者视网膜神经纤维层厚度的变化。
使用扫描激光偏振仪和共焦扫描激光断层扫描技术，测量了平均年龄为16.6±3.1岁的远视患者（n = 18）和平均年龄为17.4±3.8岁的屈光参差性弱视患者（n = 14）的视网膜神经纤维层厚度。对照组由25名平均年龄为25.7±11.8岁的健康正视者组成。对所有受试者采用两种不同技术进行3次测量，分析并比较各组每个参数的平均值。
海德堡视网膜断层扫描显示，与对照组相比，远视和弱视患者的视盘面积和杯盘比（C/D）较小，但远视组和弱视组之间无统计学显著差异。这些组中神经纤维层厚度增加无统计学意义。扫描激光偏振仪测量的各项参数也无统计学显著差异。
屈光不正可能会改变视神经乳头形态和视网膜神经纤维层厚度的定量评估。与对照组和高度远视患者相比，屈光参差性弱视患者没有相关的神经纤维层变化。
