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右心室流出道心动过速的冷冻导管消融术。

Cryocatheter ablation of right ventricular outflow tract tachycardia.

作者信息

Kurzidim Klaus, Schneider Hans-Jürgen, Kuniss Malte, Sperzel Johannes, Greiss Harald, Berkowitsch Alexander, Pitschner Heinz Friedrich

机构信息

Kerckhoff-Klinik, Department of Cardiology, Bad Nauheim, Germany.

出版信息

J Cardiovasc Electrophysiol. 2005 Apr;16(4):366-9. doi: 10.1046/j.1540-8167.2005.40571.x.

Abstract

INTRODUCTION

Cryocatheter techniques have been successfully applied to treat supraventricular tachycardia but there are no reports on their value in treating ventricular tachycardia (VT). We present our initial experience with cryocatheter ablation of right ventricular outflow tract (RVOT) tachycardia.

METHODS AND RESULTS

Cryocatheter ablation was attempted in 14 patients (13 females, age 45.9 +/- 12.7 years) who were highly symptomatic due to frequent monomorphic ventricular extrasystole (VES) or nonsustained VT originating within the RVOT. A 9-Fr, 8-mm-tip cryocatheter was used for both mapping and ablation. Cryoablation was started after localizing the arrhythmic focus by pace and activation mapping. Ablation success, defined by complete disappearance of target VES/VT acutely and during a follow-up of 9.3 +/- 1.4 weeks, was achieved in 13 of 14 patients. Ablation was successful with local activation times of 35 +/- 4 ms, 5.8 +/- 3.3 applications, 18.8 +/- 7.5 minutes total cryo time, 9.4 +/- 4.2 minutes fluoroscopy time, and 66.9 +/- 26.1 minutes total procedure time, the latter two measures showing a reduction with number of patients treated. Three patients reported slight pain related to local pressure of the catheter on the RVOT wall. No pain was described related to delivery of cryothermal energy.

CONCLUSIONS

Initial experience shows that focal VES/VT originating in the RVOT can be successfully treated using cryocatheter ablation. Acute and short term success rates, fluoroscopy times, and duration of procedure are comparable to conventional ablation techniques. A major advantage seems to be the virtual absence of ablation related pain.

摘要

引言

冷冻导管技术已成功应用于治疗室上性心动过速,但尚无关于其治疗室性心动过速(VT)价值的报道。我们介绍了我们使用冷冻导管消融右心室流出道(RVOT)心动过速的初步经验。

方法与结果

对14例患者(13例女性,年龄45.9±12.7岁)进行了冷冻导管消融尝试,这些患者因频繁的单形性室性早搏(VES)或起源于RVOT的非持续性VT而有高度症状。使用一根9F、8mm尖端的冷冻导管进行标测和消融。在通过起搏和激动标测定位心律失常病灶后开始冷冻消融。14例患者中有13例实现了消融成功,定义为目标VES/VT在急性时及9.3±1.4周的随访期间完全消失。消融成功时的局部激动时间为35±4毫秒,应用5.8±3.3次,总冷冻时间18.8±7.5分钟,透视时间9.4±4.2分钟,总手术时间66.9±26.1分钟,后两项指标随着治疗患者数量的增加而减少。3例患者报告与导管对RVOT壁的局部压迫相关的轻微疼痛。未描述与冷冻能量传递相关的疼痛。

结论

初步经验表明,起源于RVOT的局灶性VES/VT可通过冷冻导管消融成功治疗。急性和短期成功率、透视时间和手术持续时间与传统消融技术相当。一个主要优点似乎是几乎没有与消融相关的疼痛。

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