Battagel J M, Johal A, Kotecha B T
Department of Orthodontics, Dental Institute, St Bartholomew's and The Royal London School of Medicine and Dentistry, London, UK.
J Laryngol Otol. 2005 Feb;119(2):106-12. doi: 10.1258/0022215053419916.
This study assessed the effect on the upper airway during sleep nasendoscopy of mimicking the action of a mandibular advancement splint. Twenty-seven subjects with a diagnosis of sleep-disordered breathing were referred for mandibular advancement splint therapy following sleep nasendoscopy. Sleep nasendoscopy was repeated for all subjects with, and without, the appliance in situ. Follow-up sleep studies with a mandibular advancement splint in situ were undertaken for 19 individuals with significant obstructive sleep apnoea. With the mandibular advancement splint, subjective snoring levels and airway patency improved as predicted in all but one individual. Residual palatal flutter was predicted for five subjects and occurred in eight individuals. Follow-up sleep studies showed highly statistically significant reductions in median apnoea-hypopnoea index (from 28.1 to 6.1, p < 0.001). Mimicking the action of a mandibular advancement splint during sleep nasendoscopy helps considerably in the patient selection process for this form of treatment.
本研究评估了在睡眠鼻内镜检查期间模拟下颌前移矫治器的作用对上气道的影响。27名被诊断为睡眠呼吸障碍的受试者在睡眠鼻内镜检查后接受下颌前移矫治器治疗。对所有受试者在矫治器在位和不在位的情况下均重复进行睡眠鼻内镜检查。对19名患有严重阻塞性睡眠呼吸暂停的个体进行了下颌前移矫治器在位的随访睡眠研究。佩戴下颌前移矫治器后，除1名个体外，所有个体的主观打鼾水平和气道通畅度均如预期得到改善。预测有5名受试者会出现腭部残余颤动，而实际有8名个体出现。随访睡眠研究显示，呼吸暂停低通气指数中位数有高度统计学意义的降低（从28.1降至6.1，p < 0.001）。在睡眠鼻内镜检查期间模拟下颌前移矫治器的作用在这种治疗方式的患者选择过程中非常有帮助。
