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Free radicals as mediators of pancreatic islet beta-cell injury in autoimmune diabetes.

作者信息

Rabinovitch A

出版信息

J Lab Clin Med. 1992 May;119(5):455-6.

PMID:1583400
Abstract
摘要

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Free radicals as mediators of pancreatic islet beta-cell injury in autoimmune diabetes.
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Oxidative stress and redox modulation potential in type 1 diabetes.1型糖尿病中的氧化应激与氧化还原调节潜能
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Cytokine toxicity in insulin-producing cells is mediated by nitro-oxidative stress-induced hydroxyl radical formation in mitochondria.
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Heat shock induces resistance in rat pancreatic islet cells against nitric oxide, oxygen radicals and streptozotocin toxicity in vitro.热休克可诱导大鼠胰岛细胞在体外对一氧化氮、氧自由基和链脲佐菌素毒性产生抗性。
J Clin Invest. 1995 Jun;95(6):2840-5. doi: 10.1172/JCI117989.