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摄入溴化钾诱导的大鼠甲状腺微血管化分析:一项扫描电子显微镜研究。

Analysis of thyroid gland microvascularization in rats induced by ingestion of potassium bromide: a scanning electron microscopy study.

作者信息

Cozzolino Milton Fortes, Pereira Kleber Fernando, Chopard Renato Paulo

机构信息

Department of Anatomy, Biomedical Sciences Institute, University of São Paulo, Av. Lineu Prestes 2415, São Paulo 05508-900, Brazil.

出版信息

Ann Anat. 2005 Mar;187(1):71-6. doi: 10.1016/j.aanat.2004.08.004.

DOI:10.1016/j.aanat.2004.08.004
PMID:15835403
Abstract

The microvascularization of the thyroid gland in rats was studied in animals following ingestion of potassium bromide in various concentrations in drinking water (15, 50 or 100 mg/l) over a period of either 16 or 66 days. Accordingly, animals were divided into six study groups and one control group. Microvascularization was compared among the groups. The pattern of thyroidal follicle distribution within the blood vessels was evaluated by scanning electron microscopy. Animals that ingested potassium bromide presented an increased density and number of meshes in the capillary network of the follicle. The peripheral vessels showed flattening of the walls and in the central portion of the follicle, the distribution of the capillary network did not undergo any morphologic alteration.

摘要

研究了大鼠甲状腺的微血管形成情况,这些大鼠在16天或66天的时间里饮用含有不同浓度(15、50或100毫克/升)溴化钾的水。相应地,将动物分为六个研究组和一个对照组。比较了各组之间的微血管形成情况。通过扫描电子显微镜评估血管内甲状腺滤泡的分布模式。摄入溴化钾的动物滤泡毛细血管网中的网孔密度和数量增加。外周血管壁出现扁平,而在滤泡的中央部分,毛细血管网的分布未发生任何形态学改变。

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1
Analysis of thyroid gland microvascularization in rats induced by ingestion of potassium bromide: a scanning electron microscopy study.摄入溴化钾诱导的大鼠甲状腺微血管化分析:一项扫描电子显微镜研究。
Ann Anat. 2005 Mar;187(1):71-6. doi: 10.1016/j.aanat.2004.08.004.
2
Long-term action of potassium bromide on the rat thyroid gland.溴化钾对大鼠甲状腺的长期作用。
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Effect of anticonvulsant dosages of potassium bromide on thyroid function and morphology in dogs.抗惊厥剂量的溴化钾对犬甲状腺功能和形态的影响。
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Potassium bromide and the thyroid gland of the rat: morphology and immunohistochemistry, RIA and INAA analysis.溴化钾与大鼠甲状腺:形态学与免疫组织化学、放射免疫分析和仪器中子活化分析
Ann Anat. 1997 Oct;179(5):421-31. doi: 10.1016/S0940-9602(97)80041-6.
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The effect of bromide on the ultrastructure of rat thyrocytes.溴化物对大鼠甲状腺细胞超微结构的影响。
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[Effect of angiotensin on the ultrastructure of the rat thyroid gland].
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