Conway Stafford, Delplanche Curtis, Crowder Jessica, Rothrock John
University of South Alabama Headache Center, Mobile, AL 36693, USA.
Headache. 2005 Apr;45(4):355-7. doi: 10.1111/j.1526-4610.2005.05073a.x.
Chronic migraine is unfortunately both common and often resistant to treatment even with prophylactic medications known to be effective in populations with episodic migraine. We undertook an open-label study to evaluate the safety and utility of botulinum toxin type A injection therapy for patients with chronic migraine who previously had failed to respond to at least three prophylactic medications.
