Uguz Aysun, Ersoz Canan, Bolat Filiz, Gokdemir Ayse, Vardar M Ali
Department of Pathology, Cukurova University School of Medicine, Adana, Turkey.
Acta Cytol. 2005 Mar-Apr;49(2):144-8. doi: 10.1159/000326122.
To assess the diagnostic value of fine needle aspiration cytology (FNAC) in ovarian lesions.
Sixty-two fine needle aspirations of varied ovarian masses were performed between January 2000 and February 2003. Aspiration material was obtained from fresh tissues at the time of frozen section before dissection of the specimens. The slides were evaluated by a pathologist who was blinded to the gross findings and histopathologic diagnosis.
A total of 62.9% of cases were assessed as malignant and 30.6% as benign. Two false positive and 2 false negative cases occurred. In our series the overall sensitivity and specificity were 95.1% and 90.4%, respectively. Seven benign and 15 malignant lesions could be subclassified specifically.
We studied excised specimens, but since ovarian masses are reachable by laparoscopically and ultrasonographically guided aspiration, FNAC can be used for diagnoses of these lesions. If a multidisciplinary approach can be carried out in patients with ovarian lesions, cytopathologic interpretation can provide optimum benefits.
评估细针穿刺细胞学检查(FNAC)在卵巢病变中的诊断价值。
2000年1月至2003年2月期间,对62例不同的卵巢肿块进行了细针穿刺。在标本解剖前,于冰冻切片时从新鲜组织获取穿刺材料。由一位对大体检查结果和组织病理学诊断不知情的病理学家对玻片进行评估。
总共62.9%的病例被评估为恶性,30.6%为良性。出现了2例假阳性和2例假阴性病例。在我们的系列研究中,总体敏感性和特异性分别为95.1%和90.4%。7例良性病变和15例恶性病变能够被具体分类。
我们研究的是切除标本,但由于卵巢肿块可通过腹腔镜和超声引导下穿刺获取,FNAC可用于这些病变的诊断。如果对卵巢病变患者能够采用多学科方法,细胞病理学解读可带来最佳益处。