Meir Karen, Maly Bella, Shoshan Yigal, Maly Alexander, Soffer Dov
Department of Pathology, Hadassah University Hospital, Jerusalem, Israel.
Acta Cytol. 2005 Mar-Apr;49(2):195-8. doi: 10.1159/000326133.
Amyloidoma (tumoral amyloidosis) is the rarest form of central nervous system (CNS) amyloidosis.
A 51-year-old woman presented with recurrent right-sided otitis media and hearing loss. Computed tomography and magnetic resonance imaging revealed a mass in the right temporal lobe. Cytologic findings at the time of stereotactic biopsy for suspected glioma were compatible with amyloidoma. Subsequent histologic and electron microscopic findings confirmed the diagnosis of amyloidoma. Auxiliary testing ruled out systemic amyloidosis and plasma cell dyscrasia.
To our knowledge, this is the first report on the cytologic findings in a case of CNS amyloidoma.
淀粉样瘤(肿瘤性淀粉样变性)是中枢神经系统(CNS)淀粉样变性最罕见的形式。
一名51岁女性出现右侧复发性中耳炎和听力丧失。计算机断层扫描和磁共振成像显示右侧颞叶有一个肿块。疑似胶质瘤的立体定向活检时的细胞学检查结果与淀粉样瘤相符。随后的组织学和电子显微镜检查结果证实了淀粉样瘤的诊断。辅助检查排除了系统性淀粉样变性和浆细胞异常增殖症。
据我们所知,这是关于中枢神经系统淀粉样瘤病例细胞学检查结果的首次报告。