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[奇异变形杆菌对血清杀菌作用的耐药机制]

[The mechanisms of Proteus mirabilis resistance to the bactericidal action of blood serum].

作者信息

Parkhomenko L V, Koval'chuk V K, Open'ko L V

出版信息

Mikrobiol Zh (1978). 1992 Mar-Apr;54(2):81-7.

PMID:1584090
Abstract

When studying sensitivity of Proteus mirabilis to bactericide effect of blood serum the resistance to alternative way of the complement activation was found in a number of strains. The population of cells with morphologically determinable changes of the surface structures resistant to bactericide effect of the serum is formed as affected by the blood serum of the culture P. mirabilis. Proteus proteases capable to inactivate the complement components are one of the factors of P. mirabilis resistance to bactericide effect of the complement.

摘要

在研究奇异变形杆菌对血清杀菌作用的敏感性时,发现一些菌株对补体激活的替代途径具有抗性。受奇异变形杆菌培养物血清影响,形成了一群表面结构发生形态学可确定变化且对血清杀菌作用具有抗性的细胞。能够使补体成分失活的变形杆菌蛋白酶是奇异变形杆菌对补体杀菌作用产生抗性的因素之一。

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