奇异变形杆菌O3（S1959）、O9和O18菌株在正常人血清（NHS）中的存活情况与其外膜蛋白（OMP）的多样性相关。
Survival of Proteus mirabilis O3 (S1959), O9 and O18 strains in normal human serum (NHS) correlates with the diversity of their outer membrane proteins (OMPs).
作者信息
Futoma-Kołoch Bozena, Bugla-Płoskońska Gabriela, Doroszkiewicz Wlodzimierz, Kaca Wiesław
机构信息
Institute of Genetics and Microbiology, Wrocław University, Przybyszewskiego 63/77, 51-148 Wrocław, Poland.
出版信息
Pol J Microbiol. 2006;55(2):153-6.
Urinary tract infections are frequently caused by Proteus mirabilis strains. In the previous studies there were defined the complete structures of O-polysaccharide parts of lipopolysaccharides from strains: P. mirabilis O3 (S1959), P. mirabilis O9 and P. mirabilis O18. In the present study it was investigated bactericidal effect of normal human serum (NHS) to P. mirabilis strains. We also focused on the diversity of outer membrane proteins (OMPs) being separated on a gel isolated from tested strains. Serial passage of P. mirabilis O18 in 90% normal bovine serum (NBS) contributed to over-expressing some classes of OMPs.
尿路感染常由奇异变形杆菌菌株引起。在先前的研究中，已确定了来自奇异变形杆菌O3（S1959）、奇异变形杆菌O9和奇异变形杆菌O18菌株的脂多糖O-多糖部分的完整结构。在本研究中，研究了正常人血清（NHS）对奇异变形杆菌菌株的杀菌作用。我们还关注了从测试菌株中分离出的凝胶上分离的外膜蛋白（OMPs）的多样性。奇异变形杆菌O18在90%正常牛血清（NBS）中的连续传代导致某些类别的OMPs过度表达。
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