[门腔静脉吻合术后大鼠肝腺泡不同区域的超微结构研究]
[Ultrastructural study of the different zones of the rat liver acinus after portacaval anastomosis].
作者信息
Bioulac P, Dubuisson L, Saric J, Balabaud C
出版信息
C R Seances Soc Biol Fil. 1979;173(1):60-7.
PMID:158419
Abstract
Liver atrophy is a main feature in rats with a porto caval shunt. Histological studies revealed small size hepatocytes. Ultrastructural differences between periportal and centrolobular zones were noticed, in particular, the dilatation of the nuclear envelope and of the rough endoplasmic reticulum which appeared dilated, desorganized and sometimes without ribosomes, was more pronounced in the periportal zone. Hepatocytes of this zone might be more sensitive to the decrease of O2 and/or hepatotrophic factors.
摘要
肝萎缩是门腔静脉分流大鼠的主要特征。组织学研究显示肝细胞体积较小。注意到门周区和小叶中心区之间的超微结构差异，特别是核膜和粗面内质网的扩张，粗面内质网显得扩张、紊乱，有时无核糖体，在门周区更明显。该区域的肝细胞可能对氧气和/或肝营养因子的减少更敏感。
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