Kleinhans Natalia, Akshoomoff Natacha, Delis Dean C
Joint Doctoral Program in Clinical Psychology, San Diego State University, La Jolla, CA 92037, USA.
Dev Neuropsychol. 2005;27(3):379-401. doi: 10.1207/s15326942dn2703_5.
The Color-Word Interference Test, Trail Making Test, Verbal Fluency Test, and Design Fluency Test from the Delis-Kaplan Executive Function System (Delis, Kaplan, & Kramer, 2001) were administered to 12 high-functioning adults and adolescents with autistic disorder or Asperger's disorder. Each test included a switching condition in addition to baseline and/or other executive-function conditions. Participants performed significantly below average on a composite measure of executive functioning adjusted for baseline cognitive ability. Complex verbal tasks that required cognitive switching and initiation of efficient lexical retrieval strategies produced the most consistent deficits, whereas cognitive inhibition was intact. We discuss implications of these findings for understanding the neurocognitive substrates of autistic spectrum disorders.
对12名患有自闭症谱系障碍或阿斯伯格综合征的高功能成年人及青少年进行了来自德利斯-卡普兰执行功能系统(德利斯、卡普兰和克莱默,2001年)的颜色-词语干扰测试、连线测验、言语流畅性测试和图形流畅性测试。除了基线和/或其他执行功能条件外,每个测试都包括一个转换条件。在根据基线认知能力进行调整的执行功能综合测量中,参与者的表现显著低于平均水平。需要认知转换和启动有效词汇检索策略的复杂言语任务产生了最一致的缺陷,而认知抑制功能完好。我们讨论了这些发现对于理解自闭症谱系障碍神经认知基础的意义。