McKay David A, Schofield Olivia M V, Benton E Claire
Department of Dermatology, Royal Infirmary of Edinburgh, Edinburgh, UK.
Acta Derm Venereol. 2004;84(6):472-4. doi: 10.1080/00015550410018361.
Oral terbinafine is licensed for use in onychomycosis after positive confirmation of infection. We describe five cases of subacute cutaneous lupus erythematosus associated with terbinafine therapy. All cases had positive antibodies to extractable nuclear antigens, predominantly anti-Ro, and several had a history of pre-existing autoimmune disease. Terbinafine should only be prescribed after confirmation of infection by microscopy or culture.
口服特比萘芬在感染确诊后被批准用于治疗甲癣。我们描述了5例与特比萘芬治疗相关的亚急性皮肤型红斑狼疮病例。所有病例均可提取核抗原抗体阳性，主要为抗Ro抗体，部分病例有自身免疫性疾病史。特比萘芬仅应在通过显微镜检查或培养确诊感染后才予处方。
