Møller Maiken, Bygum Anette
Odense Universitetshospital, Dermato-venerologisk Afdeling I, Odense C.
Ugeskr Laeger. 2006 Dec 11;168(50):4427-8.
Cutaneous lupus erythematosus can be induced or precipitated by a variety of drugs. Among the cutaneous variants of lupus, subacute cutaneous lupus erythematosus is the one most often associated with drug intake. The time lag between drug intake and skin eruption makes the clinical association less obvious, and the condition is often overlooked. We report on a 50-year-old woman with previously diagnosed systemic lupus erythematosus who had a severe cutaneous flare-up seven weeks after starting treatment with terbinafine for suspected onychomycosis.
多种药物可诱发或促使皮肤红斑狼疮的发生。在狼疮的皮肤病变类型中,亚急性皮肤型红斑狼疮是最常与药物摄入相关的一种。药物摄入与皮疹出现之间的时间间隔使得临床关联不太明显,这种情况常常被忽视。我们报告了一名50岁的女性,她之前被诊断为系统性红斑狼疮,在因疑似甲癣开始使用特比萘芬治疗7周后,出现了严重的皮肤炎症发作。