Linn Shai
School of Public Health, Faculty of Welfare and Health Studies, Hafa University, Abba Khoushy Road, Haifa, Israel.
J Clin Epidemiol. 2005 May;58(5):450-7. doi: 10.1016/j.jclinepi.2004.07.009.
Suggesting patient-oriented ratio measures of diagnostic tests analogous to the likelihood ratios.
Algebraic equation based on Bayes' theorem.
Two new measures are suggested: the positive predictive ratio (PPR), relating the positive predictive value (PPV) to the false negative rate in the patient population, and the negative predictive ratio (NPR), relating the negative predictive value (NPV) to the false positive rate in the patient population. The new measures are analogous to likelihood ratios. These measures are calculable from the familiar 2x2 table in a selected study population or in a target (general) population. Examples are given, using published data.
PPR adds to the information given by the PPV, and NPR adds to the information given by the NPV. PPR and NPR may be more appropriate in the clinical setting than likelihood ratios.
提出类似于似然比的以患者为导向的诊断试验比率指标。
基于贝叶斯定理的代数方程。
提出了两个新指标：阳性预测比率（PPR），将阳性预测值（PPV）与患者群体中的假阴性率相关联；阴性预测比率（NPR），将阴性预测值（NPV）与患者群体中的假阳性率相关联。新指标类似于似然比。这些指标可从选定研究人群或目标（一般）人群中熟悉的2×2列联表计算得出。使用已发表的数据给出了示例。
PPR补充了PPV所提供的信息，NPR补充了NPV所提供的信息。在临床环境中，PPR和NPR可能比似然比更合适。
