Gratton Enrico, Toronov Vladislav, Wolf Ursula, Wolf Martin, Webb Andrew
University of Illinois at Urbana Champaign, Laboratory for Fluorescence Dynamics, 110 W. Green Street, Urbana, Illinois 61801, USA.
J Biomed Opt. 2005 Jan-Feb;10(1):11008. doi: 10.1117/1.1854673.
We review our most recent results on near-IR studies of human brain activity, which have been evolving in two directions: detection of neuronal signals and measurements of functional hemodynamics. We discuss results obtained so far, describing in detail the techniques we developed for detecting neuronal activity, and presenting results of a study that, as we believe, confirms the feasibility of neuronal signal detection. We review our results on near-IR measurements of cerebral hemodynamics, which are performed simultaneously with functional magnetic resonance imaging (MRI) These results confirm the cerebral origin of hemodynamic signals measured by optical techniques on the surface of the head. We also show how near-IR methods can be used to study the underlying physiology of functional MRI signals.
我们回顾了关于人类大脑活动近红外研究的最新成果，这些研究在两个方向上不断发展：神经元信号检测和功能性血液动力学测量。我们讨论了迄今为止获得的结果，详细描述了我们开发的用于检测神经元活动的技术，并展示了一项研究的结果，我们认为该结果证实了神经元信号检测的可行性。我们回顾了与功能磁共振成像（MRI）同时进行的大脑血液动力学近红外测量结果。这些结果证实了通过头部表面光学技术测量的血液动力学信号的大脑起源。我们还展示了近红外方法如何用于研究功能MRI信号的潜在生理学机制。
Zotero 插件