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99m锝-六甲基丙二胺肟脑单光子发射计算机断层扫描在1例单纯疱疹病毒性脑炎中的应用

[99mTc-HMPAO brain SPECT in a case of HSV encephalitis].

作者信息

Campos Villarino L, Serena Puig A, Romero López J, Nogueiras Alonso J M, Outomuro Pérez J

机构信息

Servicios de Medicina Nuclear, Hospital Meixoeiro, 36200 Vigo.

出版信息

Rev Esp Med Nucl. 2005 May-Jun;24(3):199-203. doi: 10.1157/13073792.

Abstract

We present a case of encephalitis caused by Herpes Simplex Virus in a 57 year old woman. The acute picture was suggestive of viral infection without associated neurological symptoms. Due to the posterior appearance of neurological focality, cerebral spinal fluid (CSF) was analyzed. It showed pleocytosis and lymphocytosis, inflammatory process data, and serological test with positivity for Simple Herpes Virus (SHV) subtypes I and II. During admission, other complementary tests were performed: EEG, CT, MRI, cerebral perfusion SPECT; the later supplied significant data regarding anatomical neuroimaging (CT, MRI) in regards to bihemispheral extension of the encephalic condition. Furthermore, after clinical discharge, persistent metabolic abnormality was demonstrated in temporal cortex, responsible for concomitant mixed aphasia.

摘要

我们报告一例57岁女性因单纯疱疹病毒引起的脑炎病例。急性期表现提示病毒感染但无相关神经症状。由于出现神经局灶性表现较晚,对脑脊液(CSF)进行了分析。结果显示有细胞增多和淋巴细胞增多、炎症过程数据,以及单纯疱疹病毒(SHV)I型和II型血清学检测呈阳性。住院期间,还进行了其他辅助检查:脑电图(EEG)、计算机断层扫描(CT)、磁共振成像(MRI)、脑灌注单光子发射计算机断层扫描(SPECT);后者提供了有关脑部病变双侧半球扩展的重要解剖神经影像学(CT、MRI)数据。此外,临床出院后,颞叶皮质出现持续性代谢异常,导致伴有混合性失语。

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