99m锝-六甲基丙二胺肟（99mTc-HMPAO）与99m锝-双半胱乙酯（99mTc-ECD）单光子发射计算机断层扫描（SPECT）在单纯疱疹病毒性脑炎中的不一致性
Discordance of technetium-99m-HMPAO and technetium-99m-ECD SPECT in herpes simplex encephalitis.
作者信息
Rieck H, Adelwöhrer C, Lungenschmid K, Deisenhammer E
机构信息
Department of Neurology, Landesnervenklinik Linz, Austria.
出版信息
J Nucl Med. 1998 Sep;39(9):1508-10.
UNLABELLED
Technetium-99m-hexamethyl propyleneamine oxime (HMPAO) and 99mTc-ethyl cysteinate dimer (ECD) accumulate in brain tissue in proportion to regional cerebral blood flow in healthy subjects and in patients with a variety of neurological diseases. We report on four patients with herpes simplex encephalitis and the discordance between these two approved cerebral perfusion imaging radiopharmaceuticals.
CONCLUSION
SPECT images showed unilateral regional increase of 99mTc-HMPAO uptake and decrease of 99mTc-ECD uptake in the affected temporal lobe.
未标记
锝-99m-六甲基丙烯胺肟（HMPAO）和锝-99m-乙基半胱氨酸二聚体（ECD）在健康受试者和患有多种神经系统疾病的患者中，在脑组织中的蓄积与局部脑血流量成比例。我们报告了4例单纯疱疹性脑炎患者以及这两种已获批的脑灌注显像放射性药物之间的不一致情况。
结论
单光子发射计算机断层扫描（SPECT）图像显示，在受影响的颞叶，锝-99m-HMPAO摄取呈单侧局部增加，而锝-99m-ECD摄取减少。
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