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8. 上气道梗阻的调查与治疗:儿童睡眠障碍I

8. Investigation and treatment of upper-airway obstruction: childhood sleep disorders I.

作者信息

Kennedy J Declan, Waters Karen A

机构信息

Department of Paediatrics, University of Adelaide, Adelaide, SA 5000, Australia.

出版信息

Med J Aust. 2005 Apr 18;182(8):419-23. doi: 10.5694/j.1326-5377.2005.tb06763.x.

Abstract

Always take a history of snoring and sleep disturbance when reviewing children in primary care, as there is evidence that episodes of hypoxia and arousal during sleep may result in deficits in memory, attention and behaviour, in addition to the well known sequelae of growth failure, developmental delay and cor pulmonale. Check for changes in behaviour affecting school progress. To investigate for possible obstructive sleep apnoea syndrome (OSAS), clinical examination, lateral neck x-ray (adenoidal hypertrophy) and overnight oximetry (desaturation episodes) are useful screening tests, but oximetry is best used in conjunction with polysomnography. A negative oximetry test does not exclude OSAS. Polysomnography is the best method for detecting and assessing the severity of OSAS in children, and is especially helpful for prioritising treatment and evaluating the risk of perioperative complications of adenotonsillectomy. Adenotonsillectomy is thought to "cure" (ie, symptoms disappear and overnight respiratory parameters are corrected) in about 80% of children with OSAS. The remaining 20% need ongoing evaluation and treatment. Further research is needed to determine the "true" prevalence of OSAS; what degrees of severity of upper-airway obstruction lead to morbidity requiring treatment; and whether the deficits in neurocognitive function associated with sleep-disordered breathing are fully correctable.

摘要

在基层医疗中对儿童进行检查时,始终要询问打鼾和睡眠障碍的病史,因为有证据表明,睡眠期间的缺氧和觉醒发作除了会导致生长发育迟缓、发育延迟和肺心病等众所周知的后遗症外,还可能导致记忆、注意力和行为方面的缺陷。检查是否有影响学业进展的行为变化。为了调查是否可能患有阻塞性睡眠呼吸暂停综合征(OSAS),临床检查、颈部侧位X光片(腺样体肥大)和夜间血氧饱和度监测(血氧饱和度下降发作)是有用的筛查测试,但血氧饱和度监测最好与多导睡眠图结合使用。血氧饱和度监测结果为阴性并不能排除OSAS。多导睡眠图是检测和评估儿童OSAS严重程度的最佳方法,对于确定治疗优先级和评估腺样体扁桃体切除术围手术期并发症的风险特别有帮助。腺样体扁桃体切除术被认为能使约80%的OSAS儿童“治愈”(即症状消失且夜间呼吸参数得到纠正)。其余20%的儿童需要持续评估和治疗。需要进一步研究以确定OSAS的“真实”患病率;上气道阻塞的何种严重程度会导致需要治疗的发病率;以及与睡眠呼吸紊乱相关的神经认知功能缺陷是否能完全纠正。

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